"My Voice"

Order a paperback or Kindle Edition or e-book of "My Voice: A Physician's Personal Experience with Throat Cancer," the complete 282 page story of Dr. Brook's diagnosis, treatment, and recovery from throat cancer.

Order a paperback or Kindle Edition or e-book of "The Laryngectomee Guide," the 170 page practical guide for laryngectomees. A free copy of the Guide can be obtained by emailing a request to customersupport.us@atosmedical.com

Obtain and/or view a video presentation, a slide presentation and an instructive manual how to ventilate laryngectomees and neck breathers (free).

Thursday, December 2, 2010

Biomarkers hold promise for early detection of head and neck cancer

New research holds promise for early detection of head and neck cancer using simple testing. The newly developed tests will be able to detect “biomarkers” which are biologic factors found within a tumor. (Chang & Califano, 2008)
Candidate biomarkers for head and neck squamous cell carcinoma include the p53 gene and its protein; microsatellite regions throughout the genome; human papillomavirus; proteins involved in cellular proliferation, apoptosis, angiogenesis, and intracellular adhesion; epithelial growth factor receptor; and various measures of immune response to cancer. (Edwards et al, 2010) Biomarkers many have potential clinical applications because they can facilitate detection of primary or recurrent cancer. These tests can be performed in saliva which is easy to obtain.
However, before these tests are used in actual clinical settings, they have to be carefully validated.