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Wednesday, April 13, 2011

Treatment of recurrent laryngeal cancer following initial nonsurgical therapy


A recent study (Agra et al. 2011) found surgery to be the preferred modality for curative treatment of recurrent laryngeal cancer after failure of nonsurgical treatments. Patients with initial early-stage cancer experiencing recurrence following radiotherapy often have more advanced-stage tumors by the time the recurrence is recognized. About one third of such recurrent cancers are suitable for conservation surgery. Endoscopic resection with the laser or open partial laryngectomy. Transoral laser surgery is currently used more frequently than open partial laryngectomy for treatment of early-stage recurrence, with outcomes equivalent to open surgery but with less associated morbidity. Laser surgery has also been employed for selective cases of advanced recurrent disease, but patient selection and expertise are required for application of this modality to rT3 tumors. In general, conservation laryngeal surgery is a safe and effective treatment for localized recurrences after radiotherapy for early-stage glottic cancer. Recurrent advanced-stage cancers should generally be treated by total laryngectomy.



2 comments:

  1. Thank you for your valuable post. We have decided to share it with our global physician audience at PhysicianNexus.com: http://physiciannexus.com/forum/topics/treatment-of-recurrent

    Jaerou Kim
    Team Member
    www.PhysicianNexus.com
    Physicians Comparing Treatments Worldwide

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  2. Thanks for this post exploring recurrent laryngeal cancer and the Agra et al (2011) study. Interesting information.

    ReplyDelete